Skin Cancer: The Facts

 

 

 

 

 

 

 

 

GENERAL

• Skin cancer is the most common form of cancer in theUnited States. More than 3.5 million skin cancers in over two million people are diagnosed annually.
• Each year there are more new cases of skin cancer than the combined incidence of cancers of the breast, prostate, lung and colon.
• One in five Americans will develop skin cancer in the course of a lifetime.
• Over the past 31 years, more people have had skin cancer than all other cancers combined.
• Nearly 800,000 Americans are living with a history of melanoma and 13 million are living with a history of nonmelanoma skin cancer, typically diagnosed as basal cell carcinoma or squamous cell carcinoma.
• Actinic keratosis is the most common precancer; it affects more than 58 million Americans. Approximately 65 percent of all squamous cell carcinomas arise in lesions that previously were diagnosed as actinic keratoses. In patients with a history of two or more skin cancers, 36 percent of basal cell carcinomas arise in lesions previously diagnosed as actinic keratoses.
• Basal cell carcinoma (BCC) is the most common form of skin cancer; an estimated 2.8 million are diagnosed annually in theUS.BCCs are rarely fatal, but can be highly disfiguring if allowed to grow.
• Squamous cell carcinoma (SCC) is the second most common form of skin cancer. An estimated 700,000 cases are diagnosed each year in theUS, resulting in approximately 2,500 deaths.
• Between 40 and 50 percent of Americans who live to age 65 will have either skin cancer at least once.
• About 90 percent of nonmelanoma skin cancers are associated with exposure to ultraviolet (UV) radiation from the sun.
• Treatment of nonmelanoma skin cancers increased by nearly 77 percent between 1992 and 2006.

MELANOMA

• One person dies of melanoma every hour (every 62 minutes).
• One in 55 people will be diagnosed with melanoma during their lifetime.
• Melanoma is the most common form of cancer for young adults 25-29 years old and the second most common form of cancer for young people 15-29 years old.
• The survival rate for patients whose melanoma is detected early, before the tumor has penetrated the skin, is about 99 percent.The survival rate falls to 15 percent for those with advanced disease.
• The vast majority of mutations found in melanoma are caused by ultraviolet radiation.
• The incidence of many common cancers is falling, but the incidence of melanoma continues to rise at a rate faster than that of any of the seven most common cancers.Between 1992 and 2004, melanoma incidence increased 45 percent, or 3.1 percent annually.
• An estimated 114,900 new cases of melanoma were diagnosed in the USin 2010 — 46,770 noninvasive (in situ) and 68,l30 invasive, with nearly 8,700 resulting in death
• Melanoma accounts for less than five percent of skin cancer cases,²⁰ but it causes more than 75 percent of skin cancer deaths.²¹
• Survival with melanoma increased from 49 percent (1950 – 1954) to 92 percent (1996 – 2003).
• Melanoma is the fifth most common cancer for males and sixth most common for females.
• Women aged 39 and under have a higher probability of developing melanoma than any other cancer except breast cancer.
• About 65 percent of melanoma cases can be attributed to ultraviolet (UV) radiation from the sun.
• One or more blistering sunburns in childhood or adolescence more than double a person’s chances of developing melanoma later in life.
• A person’s risk for melanoma doubles if he or she has had more than five sunburns at any age.
• Survivors of melanoma are about nine times as likely as the general population to develop a new melanoma.

MEN/WOMEN

• The majority of people diagnosed with melanoma are white men over age 50.
• One in 39 Caucasian men and one in 58 Caucasian women will develop melanoma in their lifetimes.
• Approximately 39,000 new cases of melanoma occur in men each year in theUS, and 29,000 in women.
• Approximately 5,700 deaths from melanoma occur in men each year in theUS, and 3,000 in women.
• Five percent of all cancers in men are melanomas; four percent of all cancers in women are melanomas.
• Adults over age 40, especially men, have the highest annual exposure to UV.
• Melanoma is one of only three cancers with an increasing mortality rate for men, along with liver cancer and esophageal cancer.
• Caucasian men over age 65 have had an 8.8 percent annual increase in melanoma incidence since 2003, the highest annual increase of any gender or age group
• Between 1980 and 2004, the annual incidence of melanoma among young women increased by 50 percent, from 9.4 cases to 13.9 cases per 100,000 women.
• The number of women under age 40 diagnosed with basal cell carcinoma has more than doubled in the last 30 years; the incidence of squamous cell carcinoma among women under age 40 has increased almost 700 percent.
• Until age 39, women are almost twice as likely to develop melanoma as men. Starting at age 40, melanoma incidence in men exceeds incidence in women, and this trend becomes more pronounced with each decade.